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enquirebio 929-MSM5-P0說(shuō)明書

　更新時(shí)間：2020-04-28　點(diǎn)擊量：727

enquirebio 929-MSM5-P0說(shuō)明書

CD14 (Monocyte / Macrophage Marker) Ultraspecific Antibody

Tested against >20,000 Human Proteins

Product NumberDescriptionPrice
929-MSM5-P0Size: 20 ug, Tag: Unconjugated$ 228.00
929-MSM5-P1Size: 100 ug, Tag: Unconjugated$ 488.00
929-MSM5-P1ABXSize: 100 ug, Tag: Unconjugated$ 488.00

SDS-PAGE Analysis Purified CD14 Mouse Monoclonal Antibody (LPSR/2385). Confirmation of Integrity and Purity of Antibody.

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SDS-PAGE Analysis Purified CD14 Mouse Monoclonal Antibody (LPSR/2385). Confirmation of Integrity and Purity of Antibody.Analysis of Protein Array containing more than 19,000 full-length human proteins using CD14 Mouse Monoclonal Antibody (LPSR/2385) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD?s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD?s) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.Formalin-fixed, paraffin-embedded human Tonsil stained with CD14 Mouse Monoclonal Antibody (LPSR/2385).

 

人類抗CD14（單核細(xì)胞/巨噬細(xì)胞標(biāo)記）抗體產(chǎn)品屬性

物種：人類

經(jīng)過(guò)測(cè)試的應(yīng)用程序： IHC。

克隆性：單克隆

抗CD14（單核細(xì)胞/巨噬細(xì)胞標(biāo)記）抗體克隆： LPSR / 2385

克隆LPSR / 2385宿主和同種型：小鼠IgG1，κ

抗人類CD14（單核細(xì)胞/巨噬細(xì)胞標(biāo)記）陽(yáng)性對(duì)照樣品： THP-1細(xì)胞和人類單核細(xì)胞。淋巴結(jié)和扁桃體。

抗體LPSR / 2385染色的細(xì)胞定位：細(xì)胞表面

緩沖液和穩(wěn)定劑： 10mM PBS，含0.05％BSA和0.05％疊氮化物。也可不帶BSA和疊氮化物。

抗體濃度： 200 ug / ml

抗體純化方法：從生物反應(yīng)器濃縮物中純化的蛋白A / G。

免疫原：人CD14蛋白的重組片段（約aa 25-148）（請(qǐng)致電以獲取更多信息。）

儲(chǔ)存條件：儲(chǔ)存于2至8 C（冷藏）。正確存放后可穩(wěn)定保存24個(gè)月。

CD14（單核細(xì)胞/巨噬細(xì)胞標(biāo)記）以前觀察到的抗體染色模式

限制與保證

inquire Bio的產(chǎn)品CD14（單核細(xì)胞/巨噬細(xì)胞標(biāo)記）MonoSpecific抗體僅可用于研究用途（僅限RUO）。正確存放后，保證該抗體可工作兩年。

CD14（單核細(xì)胞/巨噬細(xì)胞標(biāo)記）一般信息 備用名 脂多糖受體；LPS-R；LPSR；Mo2; 單核細(xì)胞分化抗原14; 骨髓細(xì)胞特異性富亮氨酸糖蛋白 分子量 55kDa的 染色體位置 在藍(lán)色冰上的船。 精選數(shù)據(jù)庫(kù)和生物信息學(xué)數(shù)據(jù) 基因符號(hào) 929 Entrez基因ID CD14 UniProt ID P08571 UniGene ID Hs163867 COSMIC ID鏈接 CD14 KEGG基因ID 衛(wèi)生署：929 CD14（單核細(xì)胞/巨噬細(xì)胞標(biāo)記）的概述。 識(shí)別55kDa的蛋白質(zhì)，稱為CD14（也稱為脂多糖受體）。CD14在單核細(xì)胞和巨噬細(xì)胞上強(qiáng)烈表達(dá)，在嗜中性粒細(xì)胞表面弱表達(dá)。CD14通過(guò)與糖基磷脂酰肌醇（GPI）相連而錨定在細(xì)胞上，并充當(dāng)LPS和LPS結(jié)合蛋白（LBP）的復(fù)合物的高親和力受體?？扇苄訡D14也與LPS結(jié)合，在生理濃度下作為L(zhǎng)PS激動(dòng)劑起作用，并且在較高濃度下具有細(xì)胞活化中的LPS拮抗作用。